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CHROMOGENIC SUBSTRATES | CHROMOGENIC SUBSTRATE S-2222
Catalog number: S820316
Description: Chromogenic substrate for factor Xa.
Package: 25 mg
Molecular wt: 741.3
Formula:
Bz-Ile-Glu(g-OR)-Gly-Arg-pNA·HCl
R=H (50%) and R=CH3 (50%)
View/Download: Insert | Chromogenic Substrates University and FAQ | Chromogenic Substrates Catalog
Methods: Trypsin Method
Illustration of Factor Xa cleaving Prothrombin (click to enlarge)
Prothrombin, the natural substrate of Factor Xa, is cleaved by Factor Xa at two positions, each proceeded by the same four amino acid sequence. Factor Xa activity can be determined by the chromogenic substrate S-2222 which is composed of the same amino acids coupled to a chromophore.
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