CHROMOGENIC SUBSTRATES | CHROMOGENIC SUBSTRATE S-2222 | ILLUSTRATION

Chromogenic Substrate S-2222 (Factor Xa cleaving Prothrombin)

Prothrombin, the natural substrate of Factor Xa, is cleaved by Factor Xa at two positions, each proceeded by the same four amino acid sequence. Factor Xa activity can be determined by the chromogenic substrate S-2222 which is composed of the same amino acids coupled to a chromophore.